Corvidia & Novo Nordisk
In what was the largest acquisition of a private company in the first half of 2020, Corvidia was sold to Novo Nordisk for $725 million upfront and up to $2.1 billion in total after earn-out.
With just a handful of highly experienced people, Corvidia took its IL-6 ligand antibody, ziltikevimab, into multiple clinical studies in cardiorenal disease. The Corvidia team pursued the drug in heart disease associated with CKD, even though the disease area is out of favor in investor circles, because the potential clinical impact of the drug is so substantial.
Cardiorenal disease remains the leading killer in the US – and IL6-driven inflammation appears to be a better predictor of poor outcomes even than cholesterol status or blood pressure. The PIII studies for the antibody were likely to cost >$250 M and many years, so the team decided to sell to Novo so that the drug's development could be optimized.