1. Key Sessions of the Week
Dr Catarina Carrao sums up the most popular on-demand sessions in each conference track across the week, including:
2. Keynote: Regulatory Quality and CMC Perspectives on mRNA Vaccines and Peptide Vaccine Adjuvants, with Insights from the Ongoing COVID-19 Pandemic
We look back at this insightful presentation delivered by Dr Ralf Wagner of Paul-Ehrlich-Institut.
3. Keynote: Circular Economy and Green Solid-Phase Peptide Synthesis
Prof. Fernando Albericio of School of Chemistry of the University of Kwazulu-Natal explained the less hazardous alternatives for peptide synthesis.
4. Keynote: Commercialising ONPATTRO (Patisiran), the First Ever RNAi Therapeutic
Dr. Eric Green of Alnylam Pharmaceuticals revealed the current strategies for the internationally approved ONPATTRO (Patisiran).
5. Poster: Fmoc-SPPS Chain Termination
Bachem's Daniel Samson illustrated how the company observed significant amounts of chain termination in Fmoc‐SPPS while synthesising the N‐terminal Xaa‐Asp‐Yaa motif.
6. Neoantigen Peptide Therapies and Personalised Vaccines
Dr. Samantha Zaroff Ph.D of Genscript discussed the use of neoantigens in personalised medicine and the challenges behind producing them.
7. On-demand Session: CMC Considerations for mRNA based Therapeutics
Dr. Jo-Anne Riley discussed analytical approaches to characterise mRNA in early-stage development to support effective therapeutic programs.
8. On-demand Session: CMC Management for Oligonucleotide Therapeutics
Bridging Research to Clinical: Ajinomoto's Toru Okamatsu presented the challenges and strategies in putting theory into practice to produce oligonucleotide therapeutics.
