The formulation step in the Lipid Nanoparticle (LNP) production is critical and needs to be scalable without losing quality. The KNAUER´s Impingement Jets Mixing (IJM) systems provide vertical solution for the scaling the formulation methods from R&D to Production. The results of the technology transfer show no changes in the particle characterization parameters, such as particle size (<100 nm, depends on payload), polydispersity (<0.1) and encapsulation efficiency (>98%).
